Wild-type RNA or protein level

These annotations can also be submitted in bulk format, see our submission guidelines

You can use these annotations to qualitatively describe whether protein or RNA levels change in wild type cells:

  • In presence of chemicals / drugs (e.g. RNA level unchanged in presence of rapamycin)
  • During a cell cycle phase (e.g. RNA absent during meiosis I)
  • During cellular response to stimulus (e.g. protein level increased during heat response)

To make an annotation click on Wild-type RNA level or Wild-type protein level on the Quick Links list, and indicate:

  • Gene: the gene concerned. See how to add genes
  • Term name: a term describing the qualitative change.
  • Annotation extensions: available once a term is selected.
    • during: the cell cycle phase / cellular response to stimulus where the qualitative change happens.
    • in presence of: a drug or chemical.
  • Evidence code: the evidence that supports the present of that feature / motif, which can come from:
    • An experiment (EXP)
    • Sequence similarity with another gene known to have the same feature (ISS). The gene must be in the session. If you want to annotate similarity to a gene from another species, let us know when you submit your curation session.
  • Comment: it's very useful for us if you indicate the figure or table where this interaction comes from.